Supplement bottle labeled 'pure encapsulations' with 'Folate 400' on a white background

Pure Encapsulations Folate 400 - 90 Capsules

$22.00
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Supplement bottle labeled 'pure encapsulations' with 'Folate 400' on a white background

Pure Encapsulations Folate 400 - 90 Capsules

$22.00

Folate 400 mcg — Metafolin® for Optimal Methylation & DNA Synthesis

Folate 400 delivers 400 mcg of Metafolin® — a naturally occurring, reduced form of folate (5-MTHF) that bypasses the MTHFR enzyme conversion step required by synthetic folic acid. This makes it the preferred form for those with MTHFR polymorphisms, who cannot efficiently convert folic acid to its active form. Metafolin is directly bioavailable and immediately usable by the body for methylation, DNA synthesis, and homocysteine metabolism.

Key Benefits

  • MTHFR-friendly — Metafolin bypasses MTHFR conversion; ideal for those with MTHFR C677T or A1298C variants
  • Methylation support — active 5-MTHF directly supports one-carbon metabolism and SAMe production
  • DNA synthesis — folate is required for nucleotide synthesis and DNA replication
  • Homocysteine metabolism — supports healthy homocysteine remethylation for cardiovascular protection
  • 90-capsule supply — a full 3-month supply at standard dosing

Why Pure Encapsulations?

Metafolin® active folate in a hypoallergenic capsule. Third-party tested for purity and potency.

Consult your healthcare provider before use, especially if pregnant, nursing, or taking medications. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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